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| Baron, Regis; Couedel, Marielle; Joret, Camille; Garen, Pierre; Truquet, Philippe; Masselin, Pierre; Bardouil, Michele; Lassus, Patrick. |
| A simple system was used to simulate the effect of alternating toxic (paralytic shellfish poisoning toxins) and non-toxic microalgal diets on oyster feeding behaviors and rates of toxin accumulation. These experimental conditions were meant to reflect, to some extent, the incoming and outgoing fluxes of toxic algae observed at the mouth of the Penze estuary (Northern Brittany, France). Physiological and toxicological parameters were estimated based oil fluorescence measurements recorded continuously at the outlet of each experimental tank, which contained a single oyster. Q(tox), this variable describes toxin uptake in oysters, it was used (instead of the toxin ingestion rate): i) in simple graphical analyses, ii) as well as in one- and two-compartment... |
| Tipo: Text |
Palavras-chave: Skeletonema costatum; Alexandrium minutum; Fluorescence; Modeling; Kinetics; Toxin uptake; Shellfish toxin; PSP. |
| Ano: 2006 |
URL: http://archimer.ifremer.fr/doc/2006/publication-1400.pdf |
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| Hess, Philipp; Abadie, Eric; Herve, Fabienne; Berteaux, Tom; Sechet, Veronique; Araoz, Romulo; Molgo, Jordi; Zakarian, Armen; Sibat, Manoella; Rundberget, Thomas; Miles, Christopher O.; Amzil, Zouher. |
| Following a review of official control data on shellfish in France, Ingril Lagoon had been identified as a site where positive mouse bioassays for lipophilic toxins had been repeatedly observed. These unexplained mouse bioassays, also called atypical toxicity, coincided with an absence of regulated toxins and rapid death times in mice observed in the assay. The present study describes pinnatoxin G as the main compound responsible for the toxicity observed using the mouse bioassay for lipophilic toxins. Using a well-characterised standard for pinnatoxin G, LC-MS/MS analysis of mussel samples collected from 2009 to 2012 revealed regular occurrences of pinnatoxin G at levels sufficient to account for the toxicity in the mouse bioassays. Baseline levels of... |
| Tipo: Text |
Palavras-chave: Cyclic imines; Shellfish toxin; Accumulation; Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS); Unexplained mouse toxicity. |
| Ano: 2013 |
URL: http://archimer.ifremer.fr/doc/00158/26960/25255.pdf |
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